The end is nigh for the people of Aegis VII. The planet is under quarantine under the order of Captain Matthias, CO of the Ishimura, and the whole colony is on emergency power only. Terrifying aliens creatures are rampaging through the colony, killing and reanimating the bodies of the dead, and the Colony Manager Carthusia lets himself be killed by one of these strange beings. The purpose is unclear but it can’t mean lives will get any better for the Aegis VII residents.